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Practical Process Development

Course Outline:

1. Introduction

2. Various Stages of Process Development 

  • Various stages and their interactions 

  • Clear objective for each stage 

3. Interactions among Modeling/Experimental Work/Synthesis 

  • Process development - A "detective" exercise 

  • Searching for clues - Experimental work 

  • Creation of hypothesis - Synthesis 

  • Analysis of scenarios - Modeling 

4. Workflow 

  • Workflow for new process 

  • Workflow for retrofit 

5. Important Elements in Experimental Work 

  • Reproducibility 

  • Analytical methods 

6. Important Elements in Process Synthesis 

  • Patent position 

  • Cost analysis 

  • Understanding the limitation 

  • Generation and evaluation of alternatives 

7. Important Elements in Modeling

  • Modeling for the appropriate level of complexity 

  • Estimation of parameters 

  • Design of experiments 

  • Optimization

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Consortium of Chemical Products and Processes
Department of Chemical Engineering
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong